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助理研究员

  • E-mail:wenlu.wl(at)gmail.com
  • 办公电话:+86-10-6275.5246(4050)
    办公地点:北京大学综合科研楼生物动态光学成像中心308室
    邮件地址:北京市海淀区颐和园路5号北京大学生物动态光学成像中心,100871
    研究组主页:
  • 理学博士,中南大学医学遗传学国家重点实验室,2004,遗传学
    医学硕士,中南大学湘雅医学院,2000,神经外科学
    医学学士,中南大学湘雅医学院,2000,临床医学(七年制本硕连读)

    工作经历
  • 2011-现在,北京大学生物动态光学成像中心,助理研究员

    2009-2010,中山大学生命科学学院,讲师

    2005-2008,北京大学生命科学学院,博士后

    主要研究方向
  • 基因组学、DNA甲基化组学和单细胞分析技术
    获奖及荣誉
    代表性论文及论著
  • 7. Wen L, Tang F. Reconstructing Complex Tissues from Single-Cell Analyses. Cell 2014, 157: 771-773 (Preview).
    6. Wen L*, Li X*, Yan L*, Tan Y*, Li R, Zhao Y, Wang Y, Xie J, Zhang Y, Song C, Yu M, Liu X, Zhu P, Li X, Hou Y, Guo H, Wu X, He C, Li R, Tang F, Qiao J. Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain. Genome Biology 2014, 15(3): R49 (*: Co-first author).
    5. Gan H*, Wen L*, Liao S*, Lin X, Ma T, Liu J, Song CX, Wang M, He C, Han C, Tang Fuchou. Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis. Nature Communications 2013, 4: 1995 (*: co-first author).
    4. Lan XJ*, Wen L *ξ, Li K, Liu XJ, Luo BP, Chen F, Xie D, Kung HF. Comparative analysis of duplicated sox21 genes in zebrafish. Development, Growth & Differentiation 2011, 53(3) :347-56. (* co-first author, ξcorresponding author)
    3. Wen L, Wei W, Gu WC, Huang P, Ren X, Zhu ZY, Lin S, Zhang B. Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish. Developmental Biology 2008, 314 (1): 84-92.
    2. Wen L, Liang DS, Wu LQ, Cai F, Pan Q, Long ZG, Dai HP, Xia K, Xia JH. Efficient protein expression from the endogenous RNA polymerase I promoter using a human ribosomal DNA targeting vector. Biochemical and Biophysical Research Communication. 2008, 367 (4): 846-51.
    1. Wen L, Wei W, Huang HG, Qi F, Dong W, Du J, Xue YL, Zheng NZ, Ren X, Huang P, Ren J, Gao W, Xiao A, Kawakami K, Zhu ZY, Zhang B, Lin S. Large-scale enhancer trapping in zebrafish using Tol2 transposon. 2006 International Zebrafish Development and Genetics Conference. (Abstract)