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庞玉宏
研究副教授

  • E-mail:pangyuhong#pku.edu.cn
  • 办公电话:+86-10-6275.8323
    办公地点:北京大学综合科研楼生物动态光学成像中心309室
    邮件地址:北京市海淀区颐和园路5号北京大学综合科研楼生物动态光学成像中心,100871
    研究组主页:http://gene.pku.edu.cn/
  • 理学博士,中科院生物物理所,2005,生物化学与分子生物学
    理学学士,吉林大学,1999,生物化学

    工作经历
  • 2013-现在,北京大学生命科学学院生物动态光学成像中心,研究副教授

    2008-2013,北京大学工学院,研究副教授

    2005-2008,美国Burnham 医学研究所Gen-Sheng Feng组,博士后

    主要研究方向
  • 基于大规模微流控芯片技术的生物工程学研究及建立在工程学基础上的微纳米生物技术方法研究。
    获奖及荣誉
  • 2006-2008,美国CIRM (California Institute for Regenerative Medicine) postdoctoral fellowship

    代表性论文及论著
  • 12. Aaron M. Streets, Xiannian Zhang, Chen Cao, Yuhong Pang, Xinglong Wu, Liang Xiong, Lu Yang, Yusi Fu, Liang Zhao,* Fuchou Tang,* Yanyi Huang.* Microfluidic single-cell whole transcriptome sequencing. PNAS 2014, published online. doi: 10.1073/pnas.1402030111

    11. Wentao Li, Tao Chen, Zitian Chen, Peng Fei, Zhilong Yu, Yuhong Pang, Yanyi Huang. Squeeze-chip: A finger controlled microfluidic flow network device and its application to biochemical assays. Lab on a Chip 2012, published online on Feb. 28, 2012. [DOI: 10.1039/C2LC40125H]

    10. Chunhong Zheng, Gui’e Chen, Yuhong Pang, Yanyi Huang. An Integrated microfluidic device for long-term culture of isolated single mammalian cells. Science China Chemistry 2012, 55(4), 502-507. (featured as front cover of the issue)

    9. Ying Zhou, Yuhong Pang, Yanyi Huang. Openly Accessible Microfluidic Liquid Handlers for Automated High-throughput Nanoliter Cell Culture. Analytical Chemistry 2012, 84(5), 2576-2584.

    8. Chunhong Zheng, Liang Zhao, Gui'e Chen, Ying Zhou, Yuhong Pang, Yanyi Huang. Quantitative Study of the Dynamic Tumor-Endothelial Cell Interactions through an Integrated Microfluidic Coculture System. Analytical Chemistry 2012, 84(4), 2088-2093.

    7. Jie Shen, Ying Zhou, Tu Lu, Junya Peng, Zhixiang Lin, Lei Huang, Yuhong Pang, Li Yu, Yanyi Huang. Lab on a Chip, 2012, 12(2), 317-324"An Integrated Chip for Immunofluorescence and Its Application to Analyze Lysosomal Storage Disorders".

    6, Wu D#, Pang Y#, Ke Y, Yu J, He Z, Tautz L, Mustelin T, Ding S, Huang Z, Feng GS. A Conserved Mechanism for Regulation of Mouse and Human Embryonic Stem Cell differentiation by Shp2 Tyrosine Phosphatase. (# co-1st author) PLoS ONE 4(3):e4914 (2009)

    5, Ke Y, Zhang E.E, Hagihara K, Wu D, Pang Y, Klein R, Curran T, Ranscht B, Feng G.S. Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. Mol Cell Biol 27(19):6706-1 (2007)

    4, Ke Y, Wu D, Princen F, Nguyen T, Pang Y, Lesperance J, Muller WJ, Oshima RG, Feng G.S. Role of Gab2 in mammary tumorigenesis and Metastasis. Oncogene 26(34):4951-60 (2007)

    3, Pang Y, Li X, Qin S, Zhang H and Chen J. Mechanism of Inhibition of Ca2+-transport activity of sarcoplsmic reticulum Ca2+-ATPase by anisodamine. Indian Journal of Biochemistry & Biophysics 43(6):351-359 (2006)

    2, Pang Y, Zhu H, Wu P, Chen J. The characterization of plasma membrane Ca2+-ATPase in rich sphingomyelin-cholesterol domains. FEBS Letters 579(11):2397-2403 (2005)

    1, Pang YH and Chen JW. Anisodamine Causes the Changes of Structure and Function in the Transmembrane Domain of the Ca2+-ATPase from Sarcoplasmic Reticulum. Biosci. Biotechol. Biochem 68 (1):126-131 (2004)