Biomedical Pioneering Innovation Center

Contact

E-mail:hesheng@biopic.pku.edu.cn
Tel:+86-010-80726688-8751
Add:Yard 28, Science Park Road, Changping District, Beijing

Lab Web：

Hesheng Liu

BIOPIC, Adjunct Professor

Resume

2021-Present Peking University, BIOPIC, Professor

2021-Present Changping Laboratory, Division of Brain Sciences, Chief Scientist

2019-2021 Medical University of South Carolina, Neuroscience, SmartState Endowed Chair Professor (tenured)

2019-2021 Medical University of South Carolina, Computational Brain Imaging Core, Director

2012-2021 Harvard Medical School, Precision Brain Imaging Laboratory, Director

2016-2021 Harvard Medical School, Radiology, Associate Professor

2012-2016 Harvard Medical School, Radiology, Assistant Professor

2009-2012 Harvard Medical School, Radiology, Instructor

2006-2009 Harvard Medical School, Radiology, Postdoctoral Fellow

2004-2006 Washington State University, Computer Science, Postdoctoral Fellow

2003，Tsinghua University，Ph.D

1997，Tsinghua University，B.S

Research Interests

The Liu Lab has long been engaged in brain functional imaging research and is one of the principal contributors to the clinical application of functional magnetic resonance imaging (fMRI) on the international stage. The lab is committed to advancing the application of brain functional imaging technology in the clinical setting for major neurological diseases. The research directions include(1) Precision brain functional mapping at individual-level. Developing reliable and accurate individualized brain functional area delineation techniques to study the fundamental cognitive functions of the brain, such as language, memory, social cognition, and emotion.;(2) Clinical translational research for major neurological diseases. Identifying functional circuits responsible for neurodegenerative, neurological, and psychiatric symptoms, and translating these brain imaging markers into clinical practice for treating brain disorders such as Parkinson’s, Alzheimer’s, Depression, Autism, Stroke, etc.;(3) Development of clinical intervention devices for major neurological diseases.

Awards and Honors

2021 Pierre Janet Writing Award, International Society for the Study of Trauma and Dissociation

2019 Smart State Endowed Chair, State of South Carolina

2013 NARSAD Young Investigator

Selected Publication

Ren J, An N, Zhang Y, Wang D, Sun Z, Lin C, Cui W, Wang W, Zhou Y, Zhang W, Hu Q, Zhang P, Hu D, Wang D, Liu H. “SUGAR: Spherical Ultrafast Graph Attention Framework for Cortical Surface Registration”, Medical Image Analysis, 2024
Ren J, Ren W, Zhou Y, Dahmani L, Duan X, Fu X, Wang Y, Pan R, Zhao J, Zhang P, Wang B, Yu W, Chen Z, Zhang X, Sun J, Ding M, Huang J, Xu L, Li S, Wang W, Xie W, Zhang H, Liu H. “Personalized functional imaging-guided rTMS on the superior frontal gyrus for post-stroke aphasia: A randomized sham-controlled trial”, Brain Stimulation, 2023
Peng X, Liu Q, Hubbard C, Wang D, Zhu W, Fox MD, Liu H., “Robust dynamic brain coactivation states estimated in individuals”, Science Advances, 2023
Trambaiolli, L. R., Peng, X., Lehman, J. F., Linn, G., Russ, B. E., Schroeder, C. E., Liu, H. #, Haber, S. N. #, “Anatomical and functional connectivity support the existence of a salience network node within the caudal ventrolateral prefrontal cortex”, Elife, 11, 2022.
Cui W, Wang Y, Ren J, Hubbard CS, Fu X, Fang S, Wang D, Zhang H, Li Y, Li L, Jiang T., Liu H. “Personalized fMRI delineates functional regions preserved within brain tumors”. Annals of neurology, 2021.
Wang D., Peng X., Pelletier-Baldelli A., Orlov N., Farabaugh A., Nasr S., Eryilmaz H., Fava M., Holmes A., Roffman J.L., Liu H. #, Holt D. #, “Altered temporal, but intact spatial, features of transient network dynamics in psychosis”, Molecular Psychiatry, 2021
Yan Y., Dahmani L., Ren J., Shen L., Peng X., Wang R., He C., Jiang C., Gong C., Tian Y., Zhang J., Guo Y., Lin Y., Li S., Wang M., Li L., Hong B., Liu H., "Reconstructing lost BOLD signal in individual participants using deep machine learning", Nature Communications, 2020
Stoecklein S., Hilgendorff A., Li M., Förster K., Flemmer A.W., Galiè F., Wunderlich S., Wang D., Stein S., Ehrhardt H., Dietrich O., Zou Q., Zhou S., Ertl-Wagner B., Liu H. “Variable Functional Connectivity Architecture of the Preterm Human Brain: Impact of Developmental Cortical Expansion and Maturation” Proc Natl Acad Sci USA, 2020
Lebois L., Li M., Baker J.T., Wolff J., Wang D., Grinspoon E., Winternitz S., Ren J., Ressler K., Liu H. #, Kaufman M. #, “Large-scale functional brain network architecture changes associated with trauma-related dissociation”, Am. J. Psychiatry, 2020
Shen L., Jiang C., Hubbard C.S., Ren J., He C., Wang D., Dahmani L., Guo Y., Liu Y., Xu S., Meng F., Zhang J., Liu H.# , Li L. # “Subthalamic nucleus deep brain stimulation modulates two distinct neurocircuits”, Annals of Neurology, 2020
Stoecklein, V.M., Stoecklein, S., Galiè, F., Ren, J., Schmutzer, M., Unterrainer, M., Albert, N.L., Kreth, F.W., Thon, N., Liebig, T. and Ertl-Wagner, B., Tonn J.C., Liu H. “Resting-state fMRI Detects Alterations in Whole Brain Connectivity Related to Tumor Biology in Glioma Patients.” Neuro-Oncology. 2020
Liu H., Xiaolong Peng X., Dahmani L., Wang H. , Zhang M., Shan Y., Rong D., Guo Y., Li J., Li N., Wang L., Lin Y., Pan R. Lu J., Wang D., “Different stroke-induced striatal lesions lead to differential structural brain reorganization”, Neurology, 2020
Wang D., Li M., Wang M., Schoppe F., Ren J., Chen H., Ongur D., Baker J.T., Liu H., “Individual-specific functional connectivity markers track dimensional and categorical features of psychotic illness”, Molecular Psychiatry, 2020