Add:Yard 28, Science Park Road, Changping District, Beijing

Lab Web:

Hesheng Liu
BIOPIC, Adjunct Professor

2021-Present  Peking University, BIOPIC, Professor 

2021-Present  Changping Laboratory, Division of Brain Sciences, Chief Scientist

2019-2021    Medical University of South Carolina, Neuroscience, SmartState Endowed Chair Professor (tenured)

2019-2021   Medical University of South Carolina, Computational Brain Imaging Core, Director

2012-2021   Harvard Medical School, Precision Brain Imaging Laboratory, Director

2016-2021   Harvard Medical School, Radiology, Associate Professor

2012-2016   Harvard Medical School, Radiology, Assistant Professor

2009-2012   Harvard Medical School, Radiology, Instructor

2006-2009   Harvard Medical School, Radiology, Postdoctoral Fellow

2004-2006   Washington State University, Computer Science, Postdoctoral Fellow

2003,Tsinghua University,Ph.D

1997,Tsinghua University,B.S

Research Interests

The Liu Lab focuses on development of brain imaging technologies and aims at improving treatments for patients with brain disorders. The research areas include (1) Precision brain functional mapping at the single-subject level, and understanding brain networks that underlie cognition, emotion, memory, language and other basic functions; (2) Identifying functional circuits responsible for neurological and psychiatric symptoms and translating these brain imaging markers into clinical practice for treating brain disorders such as Depression, Autism, Stroke, Parkinson’s, etc; (3) Establishing personalized neuromodulation strategies based on cutting-edge imaging technologies.

Awards and Honors

2021 Pierre Janet Writing Award, International Society for the Study of Trauma and Dissociation

2019 Smart State Endowed Chair, State of South Carolina

2013 NARSAD Young Investigator

Selected Publication

*indicates corresponding or co-corresponding authors, # indicates equal contributed first authors

Google Scholar:


1.Peng X, Liu Q, Hubbard C, Wang D, Zhu W, Fox MD, Liu H., Robust dynamic brain coactivation states estimated in individuals, Science Advances, 2022

2.Trambaiolli, L. R., Peng, X., Lehman, J. F., Linn, G., Russ, B. E., Schroeder, C. E., Liu, H. #, Haber, S. N. #, “Anatomical and functional connectivity support the existence of a salience network node within the caudal ventrolateral prefrontal cortex”, Elife, 11, 2022.

3.Cui W, Wang Y, Ren J, Hubbard CS, Fu X, Fang S, Wang D, Zhang H, Li Y, Li L, Jiang T., Liu H. “Personalized fMRI delineates functional regions preserved within brain tumors”. Annals of neurology, 2021.

4.Wang D., Peng X., Pelletier-Baldelli A., Orlov N., Farabaugh A., Nasr S., Eryilmaz H., Fava M., Holmes A., Roffman J.L., Liu H. #, Holt D. #, “Altered temporal, but intact spatial, features of transient network dynamics in psychosis”, Molecular Psychiatry, 2021

5.Yan Y., Dahmani L., Ren J., Shen L., Peng X., Wang R., He C., Jiang C., Gong C., Tian Y., Zhang J., Guo Y., Lin Y., Li S., Wang M., Li L., Hong B., Liu H., "Reconstructing lost BOLD signal in individual participants using deep machine learning", Nature Communications, 2020

6.Stoecklein S., Hilgendorff A., Li M., Förster K., Flemmer A.W., Galiè F., Wunderlich S., Wang D., Stein S., Ehrhardt H., Dietrich O., Zou Q., Zhou S., Ertl-Wagner B., Liu H. “Variable Functional Connectivity Architecture of the Preterm Human Brain: Impact of Developmental Cortical Expansion and Maturation” Proc Natl Acad Sci USA, 2020

7.Lebois L., Li M., Baker J.T., Wolff J., Wang D., Grinspoon E., Winternitz S., Ren J., Ressler K., Liu H. #, Kaufman M. #, “Large-scale functional brain network architecture changes associated with trauma-related dissociation”, Am. J. Psychiatry, 2020

8.Shen L., Jiang C., Hubbard C.S., Ren J., He C., Wang D., Dahmani L., Guo Y., Liu Y., Xu S., Meng F., Zhang J., Liu H.# , Li L. # “Subthalamic nucleus deep brain stimulation modulates two distinct neurocircuits”, Annals of Neurology, 2020

9.Stoecklein, V.M., Stoecklein, S., Galiè, F., Ren, J., Schmutzer, M., Unterrainer, M., Albert, N.L., Kreth, F.W., Thon, N., Liebig, T. and Ertl-Wagner, B., Tonn J.C., Liu H. “Resting-state fMRI Detects Alterations in Whole Brain Connectivity Related to Tumor Biology in Glioma Patients.” Neuro-Oncology. 2020

10.Liu H., Xiaolong Peng X., Dahmani L., Wang H. , Zhang  M., Shan  Y., Rong D., Guo Y., Li J., Li  N., Wang L., Lin Y., Pan R. Lu J., Wang D., “Different stroke-induced striatal lesions lead to differential structural brain reorganization” Neurology, 2020

11.Wang D., Li M., Wang M., Schoppe F., Ren J., Chen H., Ongur D., Baker J.T., Liu H., “Individual-specific functional connectivity markers track dimensional and categorical features of psychotic illness”, Molecular Psychiatry, 2020

12.Li M., Wang D., Ren J., Langs G., Stoecklein S., Brennan B.P., Lu J., Chen H., Liu H., “Performing group-level functional image analyses based on homologous functional regions mapped in individuals”, PLoS Biology, 2019

13.Tang W.#, Liu H.#, Douw L., Kramer M.A., Eden U.T., Hämäläinen M.S., Stufflebeam S.M., Dynamic connectivity modulates local activity in the core regions of the default-modeProc Natl Acad Sci USA2017

14.Wang D, Buckner RL, Fox MD, Holt DJ, Holmes AJ, Mueller S, Langs G, Pan R, Qian T, Li K, Baker J, Stufflebeam SM, Wang K, Wang X, Hong B, Liu H. “Parcellating Cortical Functional Networks in Individuals”. Nature Neuroscience, 2015

15.Mueller S., Wang D., Pan R., Holt D., Liu H., “Abnormalities in hemispheric specialization of caudate nucleus connectivity in schizophrenia”, JAMA Psychiatry, 2015

16.Zeng L., Wang D., Fox M.D., Sabuncu M., Hu D., Ge M., Buckner R.L., Liu H., “Neurobiological basis of head motion in brain imaging”. Proc Natl Acad Sci USA, 2014

17.Mueller S., Wang D., Fox M.D., Yeo B.T.T., Sepulcre J., Sabuncu M.R., Shafee R., Lu J., Liu H., “Individual variability in functional connectivity architecture of the human brain”, Neuron, 2013

18.Liu H., Stufflebeam S.M., Sepulcre J., Hedden T., Buckner R.L., “Evidence from Intrinsic Activity that Asymmetry of the Human Brain is Controlled by Multiple Factors”, Proc Natl Acad Sci USA, 2009.

19.Liu. H., Agam Y., Madsen J.R., Kreiman G., “Timing, timing, timing: fast decoding of object information from intracranial field potentials in human visual cortex”, Neuron, 2009.