Add:Yard 28, Science Park Road, Changping District, Beijing

Lab Web:

Hesheng Liu
BIOPIC, Adjunct Professor

2021-Present  Peking University, BIOPIC, Professor 

2021-Present  Changping Laboratory, Division of Brain Sciences, Chief Scientist

2019-2021    Medical University of South Carolina, Neuroscience, SmartState Endowed Chair Professor (tenured)

2019-2021   Medical University of South Carolina, Computational Brain Imaging Core, Director

2012-2021   Harvard Medical School, Precision Brain Imaging Laboratory, Director

2016-2021   Harvard Medical School, Radiology, Associate Professor

2012-2016   Harvard Medical School, Radiology, Assistant Professor

2009-2012   Harvard Medical School, Radiology, Instructor

2006-2009   Harvard Medical School, Radiology, Postdoctoral Fellow

2004-2006   Washington State University, Computer Science, Postdoctoral Fellow

2003,Tsinghua University,Ph.D

1997,Tsinghua University,B.S

Research Interests

The Liu Lab has long been engaged in brain functional imaging research and is one of the principal contributors to the clinical application of functional magnetic resonance imaging (fMRI) on the international stage. The lab is committed to advancing the application of brain functional imaging technology in the clinical setting for major neurological diseases. The research directions include(1) Precision brain functional mapping at individual-level. Developing reliable and accurate individualized brain functional area delineation techniques to study the fundamental cognitive functions of the brain, such as language, memory, social cognition, and emotion.;(2) Clinical translational research for major neurological diseases. Identifying functional circuits responsible for neurodegenerative, neurological, and psychiatric symptoms, and translating these brain imaging markers into clinical practice for treating brain disorders such as Parkinson’s, Alzheimer’s, Depression, Autism, Stroke, etc.;(3) Development of clinical intervention devices for major neurological diseases.

Awards and Honors

2021 Pierre Janet Writing Award, International Society for the Study of Trauma and Dissociation

2019 Smart State Endowed Chair, State of South Carolina

2013 NARSAD Young Investigator

Selected Publication
  1. Ren J, An N, Zhang Y, Wang D, Sun Z, Lin C, Cui W, Wang W, Zhou Y, Zhang W, Hu Q, Zhang P, Hu D, Wang D, Liu H. “SUGAR: Spherical Ultrafast Graph Attention Framework for Cortical Surface Registration”, Medical Image Analysis, 2024
  2. Ren J, Ren W, Zhou Y, Dahmani L, Duan X, Fu X, Wang Y, Pan R, Zhao J, Zhang P, Wang B, Yu W, Chen Z, Zhang X, Sun J, Ding M, Huang J, Xu L, Li S, Wang W, Xie W, Zhang H, Liu H. “Personalized functional imaging-guided rTMS on the superior frontal gyrus for post-stroke aphasia: A randomized sham-controlled trial”, Brain Stimulation, 2023
  3. Peng X, Liu Q, Hubbard C, Wang D, Zhu W, Fox MD, Liu H., “Robust dynamic brain coactivation states estimated in individuals”, Science Advances, 2023
  4. Trambaiolli, L. R., Peng, X., Lehman, J. F., Linn, G., Russ, B. E., Schroeder, C. E., Liu, H. #, Haber, S. N. #, “Anatomical and functional connectivity support the existence of a salience network node within the caudal ventrolateral prefrontal cortex”, Elife, 11, 2022.
  5. Cui W, Wang Y, Ren J, Hubbard CS, Fu X, Fang S, Wang D, Zhang H, Li Y, Li L, Jiang T., Liu H. “Personalized fMRI delineates functional regions preserved within brain tumors”. Annals of neurology, 2021.
  6. Wang D., Peng X., Pelletier-Baldelli A., Orlov N., Farabaugh A., Nasr S., Eryilmaz H., Fava M., Holmes A., Roffman J.L., Liu H. #, Holt D. #, “Altered temporal, but intact spatial, features of transient network dynamics in psychosis”, Molecular Psychiatry, 2021
  7. Yan Y., Dahmani L., Ren J., Shen L., Peng X., Wang R., He C., Jiang C., Gong C., Tian Y., Zhang J., Guo Y., Lin Y., Li S., Wang M., Li L., Hong B., Liu H., "Reconstructing lost BOLD signal in individual participants using deep machine learning", Nature Communications, 2020
  8. Stoecklein S., Hilgendorff A., Li M., Förster K., Flemmer A.W., Galiè F., Wunderlich S., Wang D., Stein S., Ehrhardt H., Dietrich O., Zou Q., Zhou S., Ertl-Wagner B., Liu H. “Variable Functional Connectivity Architecture of the Preterm Human Brain: Impact of Developmental Cortical Expansion and Maturation” Proc Natl Acad Sci USA, 2020
  9. Lebois L., Li M., Baker J.T., Wolff J., Wang D., Grinspoon E., Winternitz S., Ren J., Ressler K., Liu H. #, Kaufman M. #, “Large-scale functional brain network architecture changes associated with trauma-related dissociation”, Am. J. Psychiatry, 2020
  10. Shen L., Jiang C., Hubbard C.S., Ren J., He C., Wang D., Dahmani L., Guo Y., Liu Y., Xu S., Meng F., Zhang J., Liu H.# , Li L. # “Subthalamic nucleus deep brain stimulation modulates two distinct neurocircuits”, Annals of Neurology, 2020
  11. Stoecklein, V.M., Stoecklein, S., Galiè, F., Ren, J., Schmutzer, M., Unterrainer, M., Albert, N.L., Kreth, F.W., Thon, N., Liebig, T. and Ertl-Wagner, B., Tonn J.C., Liu H. “Resting-state fMRI Detects Alterations in Whole Brain Connectivity Related to Tumor Biology in Glioma Patients.” Neuro-Oncology. 2020
  12. Liu H., Xiaolong Peng X., Dahmani L., Wang H. , Zhang M., Shan Y., Rong D., Guo Y., Li J., Li N., Wang L., Lin Y., Pan R. Lu J., Wang D., “Different stroke-induced striatal lesions lead to differential structural brain reorganization”, Neurology, 2020
  13. Wang D., Li M., Wang M., Schoppe F., Ren J., Chen H., Ongur D., Baker J.T., Liu H., “Individual-specific functional connectivity markers track dimensional and categorical features of psychotic illness”, Molecular Psychiatry, 2020