Title: Applications of Optical Coherence Tomography and Microscopy  in 

       Biology and Medicine

       光学相干层析及显微技术在生物和医学中的应用

Speaker: Chao Zhou, PhD

         Lehigh University

Time: May 13th, 19:00

Venue: Rm. 302, Integrated Science Research Center

Abstract:

Optical coherence tomography (OCT) is a powerful tool for assessing tissue architectural morphology. It enables three-dimensional (3D) imaging with micron-scale resolutions, and can be performed in vivo and in real-time without the need to remove and process specimens. OCM combines OCT with confocal microscopy in order to achieve high transverse resolutions, thus enabling 3D visualization of cellular features. OCT has gradually become the standard-of-care to non-invasively evaluate retinal pathology in ophthalmology clinics.Recently, applications of OCT and OCM have started to grow in other clinical and scientific areas.In this seminar, novel applications using OCT and OCM for investigation of heart development in Drosophila, evaluation of seizure-induced neuronal changes in brain slices, cancer diagnosis in pathology laboratory, and recent technical advances (e.g. space-division multiplexing OCT) will be presented.

Biography:

Dr. Chao Zhou obtained his Ph.D. degree in physics in 2007 from the University of Pennsylvania, where he worked with Professor Arjun G. Yodh on the development of diffuse optical spectroscopy and imaging techniques.In August 2007, Dr. Zhou joined Professor James G. Fujimoto's Laser Medicine and Medical Imaging Group at the Massachusetts Institute of Technology as a postdoctoral associate. Since then, he has been working on the development of Optical Coherence Tomography (OCT) and Optical Coherence Microscopy (OCM) technologies. In 2012, Dr. Zhou joined the faculty at Lehigh University as an assistant professor in electrical engineering and bioengineering. Dr. Zhou has extensive experience in the field of biomedical optical imaging and has contributed to the development and validation of novel modalities for the imaging of humans and animals with various applications ranging from measuring the brain function to monitoring cancer treatments. Dr. Zhou has published 47 peer-reviewed journal articles, and is a member of the International Society for Optical Engineering, American Heart Association, and the International Society for Cerebral Blood flow and Metabolism. Dr. Zhou is a recipient of numerous honors and awards, including the National Institute of Health (NIH) Pathway to Independence Award.