联系方式

办公电话:+86-010-62751674
办公地点:北京大学综合科研楼生物医学前沿创新中心311室
邮件地址:北京市海淀区颐和园路5号北京大学综合科研楼,100871

研究组主页:http://bicmr.pku.edu.cn/~gehao/

葛颢
BIOPIC 研究员
个人履历

2011-现在,北京大学生物医学前沿创新中心(BIOPIC),研究员

2022-现在,北京国际数学研究中心,长聘教授

2018-2022,北京国际数学研究中心,长聘副教授

2011-2017,北京国际数学研究中心,副教授

2010-2011,哈佛大学化学与生物化学系,访问学者

2010-2011,复旦大学数学科学学院,副教授

2008-2009,复旦大学数学科学学院,讲师

2008,北京大学,理学博士

2004,北京大学,理学学士

主要研究方向

随机过程和统计学与物理、化学、生物的交叉。随机过程和统计学已经广泛应用于物理、化学和生物的各个角落,并随着近些年来实验技术的突飞猛进而有越来越流行的趋势。我们希望通过深入研究和应用随机过程和统计学模型,尝试研究和回答物理、化学和生物学科中的一些问题,试图给出更深刻以及更定量的结果。 

获奖及荣誉

2022,NSFC杰出青年基金

2017,北京大学黄廷芳/信和青年杰出学者奖

2016,NSFC优秀青年基金

2010,全国优秀博士论文

2009,中国数学会"家庆数学奖"(优秀博士论文奖)

代表性论文及论著
  1. Guo, X.L., Tang, T., Duan, M.X., Zhang, L.* and Ge, H.*: The Nonequilibrium Mechanism of Noise-Enhanced Drug Synergy in HIV Latency Reactivation. iScience 25,104358 (2022) 
  2. Qian, H. and Ge, H.: Stochastic Chemical Reaction Systems in Biology. in Lecture Notes on Mathematical Modeling in the Life Sciences (LMML) series. Springer (2021)
  3. Ge, H., Jia, C. and Jin, X.: Martingale structure for general thermodynamic functionals of diffusion processes under second-order averaging. Journal of Statistical Physics 184:17 (2021)
  4. Hao Ge*, Pingping Wu, Hong Qian and Xiaoliang Sunney Xie*: Relatively slow stochastic gene-state switching in the presence of positive feedback significantly broadens the region of bimodality through stablizing the uninduced phenotypic state. Plos Computational Biology 14(3): e1006051 (2018)
  5. Hao Ge*, Hong Qian and Xiaoliang Sunney Xie*: Stochastic phenotype transition of a single cell in an intermediate region of gene state switching. Physical Review Letters 114, 078101 (2015)
  6. Huiyi Chen, Katsuyuki Shiroguchi, Hao Ge* and Xiaoliang Sunney Xie*: Genome-wide study of mRNA degradation and transcript elongation in E. coli. Molecular Systems Biology 11: 781 (2015)
  7. Shasha Chong, Chongyi Chen, Hao Ge and Xiaoliang Sunney Xie*: Mechanism of transcriptional bursting in bacteria. Cell 158, 314–326 (2014)
  8. Hao Ge*, Min Qian* and Hong Qian*: Stochastic theory of nonequilibrium steady states. Part II: Applications in chemical biophysics. Physics Report 510, 87-118 (2012)
  9. Hao Ge* and Hong Qian*: The physical origins of entropy production, free energy dissipation and their mathematical representations. Physical Review E 81, 051133 (2010)
  10. Hao Ge* and Hong Qian*: Thermodynamic limit of a nonequilibrium steady state: Maxwell-type construction for a bistable biochemical system. Physical Review Letters 103, 148103 (2009)